Endocrine Abstracts

Introduction: Tertiary hyperparathyroidism can be developed in cases of persistent or non-curable secondary hyperparathyroidism or in any other case of long-standing hypocalcemia that leads to the autonomous function of at least one parathyroid gland. We present a case of a man with tertiary hyperparathyroidism and excessive maxilla swelling and extensive bone lesions.Presentation: A 32 years old man, with chronic renal failure on dialysis for twelve yea...

Introduction: Effective gestational diabetes mellitus (GDM) management is pivotal for reducing delivery complications for both mother and offspring, since a linear and continuous association between blood glucose and unfavorable outcomes has been extensively reported. The aim of present study was to investigate possible factors affecting GDM treatment goals.Methods: We retrospectively evaluated 136 consecutive patients with GDM, treated in our department...

Introduction: Effective acromegaly treatment in the era of somatostatin analog therapy may initially seem easy to apply. Several factors, modifiable or not, may be involved in every patient’s treatment. The aim of this study was to evaluate possible factors affecting effective acromegaly treatment.Methods: From the original pool of 25 patients, that were diagnosed with acromegaly in our department during the last 15 years, 18 are currently being fol...

Introduction: Most thyroid neoplasms arise from follicular cells and are well differentiated. We present an interesting case of a rare first manifestation of Papillary Thyroid Carcinoma (PTC) as a cervical cystic mass, as well as the therapeutic approach.Material-method: A 29 year-old-male, without personal or family history for PTC and no history of neck radiation referred to our department because of a slow growing right lateral cervical mass in the la...

Introduction: TSI (Thyroid Stimulating Immunoglobulin) antibodies are a form of immunoglobulin G (IgG) that can bind to thyrotropin receptors on the thyroid gland causing over-production of thyroid hormones and hyperthyroidism. The presence of positive TSI is considered pathognomonic for Graves’ disease. Although the association between Graves’ disease and thyroid cancer (TC) has been reported in previous studies, the association between the levels of TSI antibodies ...

Introduction: Adrenal cystic lesions are rare. Differential diagnoses include pseudocysts, echinococcal cysts, hemangiomas, cystic pheochromocytomas, adrenal hematomas and lymphangiomas. We present here a rare case of an adrenal lymphangioma.Case report: A 35-year old man was referred to our department for investigation of a right adrenal cystic mass, incidentally found during an abdominal ultrasound. The patient was completely asymptomatic and had a med...

Introduction: Stress is a known risk factor for the development of Graves’ disease. We have previously described the role of bereavement as an inducing factor for Graves’ disease. Bereavement as an inducing factor for Graves’ disease was shown to affect primarily female patients after the loss of a loved one. However, it appears that other stressful life events may also cause Graves’ disease.Aim: The aim of the study was to describe t...

Background and aims: Gestational diabetes (GD) is closely related to unbalanced zinc (Zn) and cooper (Cu) serum levels. The aim of this study was to investigate serum zinc and cooper levels in relation to the metabolic profile, and the impact on fetal development in a cohort of gestational diabetes GD(N) neonates and their mothers GD(M) compared to normal pregnancies.Material and Methods: Prospective controlled study in a tertiary Academic medical center...

Introduction: Patients diagnosed with DTC have excellent prognosis. A small percentage of patients with disease persistence do not respond to treatment with RAI (RAI-refractory DTC) and have low median survival (3.5 years). We investigated the prognostic factors and the disease course in patients with RAI-refractory DTC.Methods: Of all DTC patients (n=1160) followed-up in our department in recent years, 800 received RAI treatment and were classified in 2...

Background: Intestinal metaplasia (IM) of the gastric mucosa is a relatively frequent precancerous lesion. The aim of the study was to assess the prevalence and the kind of IM and also to find parameters that could predict the presence of IM in gastric neuroendocrine neoplasms type 1 (GNEN1).Methods: Fifty-nine (45 females) patients with GNEN1 were retrospectively studied. All patients included in the study had positive parietal-cell antibodies. All pati...